Does Prevagen Really Work?

Why did the makers of Prevagen settle a class action lawsuit in 2020 with the FTC over deceptive business practices and false advertising?

A couple of weeks ago, I released a video on a controversial Alzheimer’s drug that used the same scam: Controversy Around FDA’s Approval of Biogen Alzheimer’s Drug, Aducanumab ( ).

With supplements these days, it’s the Wild West. See, for example, Supplement Regulation and Side Effects: Efforts to Suppress the Truth ( ).

For more on how to live your longest, healthiest life, preorder my new book How Not to Age ( ). (As always, all proceeds I receive from all of my books ( ) are donated to charity.)

New subscribers to our e-newsletter always receive a free gift. Get yours here: .

Have a question about this video? Leave it in the comment section at and someone on the team will try to answer it.
UPDATE: We are currently testing the removal of the comment section across all video pages on the website until October, and it will either be reinstated thereafter or removed permanently based on the results. Please feel free to continue your discussions by commenting on our YouTube channel and social media accounts, where we will have Health Support volunteers available to address questions.

Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at . You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics.

Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM

Captions for this video are available in several languages; you can find yours in the video settings. View important information about our translated resources:

• Subscribe:
• Donate:
• Podcast :
• Books:
• Shop:
• Facebook:
• Twitter:
• Instagram:

Dave McKinnon

  • Adina Harper says:

    Thank you so much for keeping us enlightened to the underworkings of big pharmacies and the realities of research studies! 🙏

  • mQB3GofJzKKo7nZx says:

    There is a lot of money to be made scamming old people.

  • Adipose Rex says:

    So rare to have a nutrition expert on youtube. It’s a needle in a haystack. Thank you, Dr. over the counter drugs are still not tested by the USDA.

  • Joe Dirt says:

    Never heard of it but I hope the makers of it are behind bars some day.

  • dnvsrz dnvsrz says:

    “A 2019 survey by Pew found that more than half believed that the Food and Drug Administration requires supplements be tested for safety, BUT THAT ISNT TRUE.” Are vaccines considered supplements? safe and effective.

  • KC says:

    Eat whole foods and take B12. Everything else is unnecessary.

  • charleskra says:

    But the commercial features an actor dressed as a pharmacist recommending it, so it must work! HA!

  • tamcon72 says:

    It’s outrageous that the makers of products like this, both pharmaceuticals and supplements, can outright LIE about the efficacy of their product and still rake in the profits. Pharmaceutical companies especially should not be publicly traded entities beholden to shareholders–that’s almost certainly a main motivation for deceit like that from the makers of Prevagen–and should be heavily regulated. They apparently are not, currently. Thanks for posting NF team!

  • Stan Levox says:

    I get this question probably like once a month with some of my clients. The answer is no, they’re all also corporate studies. Also these are older seniors with limited incomes they target.

  • Julie Desnick says:

    Is there a way to assure you are buying the real, unadulterated thing when buying supplements?

  • nevadaxtube says:

    The video begs the question: are there any supplements that boost cognition or memory?

  • Tyler 'Skye' says:

    2:32 Wait, what!?
    How is that even possible, unless there were people in their pocket in court?

  • Lo Rah says:

    👍 Whole food plant based for the environment and health; vegan for the victims!

  • Maximus Grandis says:

    This was so timely! I was tempted to get this for my aging mother for the holidays after hearing the drumbeat of ads from the company on the radio. Also, I was recently arguing with a writer who submits fitness and exercise columns regarding the supplements he was recommending. I was trying to explain that the supplement market is woefully under-regulated and could be dangerous advice for our readers, but he was so dug in that I thought he may be getting a kickback from one of the companies.

  • andrew pawley says:

    I love this channel!

  • Catherine Wilson says:

    Thank you for your vigilance ❣️

  • Alex says:

    Now we know the Dr. isn’t a regular Jeopardy watcher 😁, there are adverts for Prevagen every episode

  • Kristina Rutkute says:

    Reminds me of a wrinkle-reducing cream my friend used. She said it was “scientifically proven” to work. I pulled the ONLY paper the manufacturer cited on their website. The p value between the cream and placebo was 0.4 (not 0.04, but yes, 0.4), but it did not prevent them from advertising their “scientific evidence”.

  • Paul Cohen says:

    Ok, so proteins are too large to get past the digestive system but what about peptides? I’ve recently heard about ones like Dihexa, RG3, FGL and a few others that are creating a stir.

    • says:

      Hi, @paulcohen6727! It’s not that the proteins are too large to get past the digestive system, but that the normal process of digestion breaks them down, as it’s supposed to do. With regard to peptides, according to the authors of this article, “Many studies have provided potential data concerning the characteristics and structure-activity relationships of memory-enhancing peptides. When considering the proof of efficacy of these plant-based peptides in humans as neurological treatment options, it is necessary to accumulate evidence concerning their bioavailability and permeability through blood-brain barrier (BBB).” Basically, as Dr. Greger likes to say, “We don’t know, until we put it to the test.” You can find everything on our site related to brain health here: I hope that helps!
      —Christine Kestner, MS, CNS, LDN, MPH, Health Support Volunteer

  • Kill Team Academy says:

    I would love to hear Dr. Gregor do a similar analysis of NMN and NAD supplements!

  • >